630721

6-Aminoindole

97%

• Synonyme(s) : Indol-6-ylamine, NSC 82379
• Formule empirique (notation de Hill): C₈H₈N₂
• Numéro CAS: 5318-27-4
• Poids moléculaire : 132.16
• Numéro MDL: MFCD02093959
• Code UNSPSC : 12352100
• ID de substance PubChem : 24882337
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: 97%
• Forme: solid
• Pf: 75-79 °C
• Température de stockage: −20°C
• Chaîne SMILES: Nc1ccc2cc[nH]c2c1
• InChI: 1S/C8H8N2/c9-7-2-1-6-3-4-10-8(6)5-7/h1-5,10H,9H2
• Clé InChI: MIMYTSWNVBMNRH-UHFFFAOYSA-N

Description

Application

Reactant for preparation of:

• Inhibitors of mammalian target of rapamycin (mTOR ) protein
• Inhibitors of the AcrAB-TolC efflux pump
• Inhibitors of Gli1-mediated transcription in the Hedgehog pathway
• Potent DNA-topoisomerase II poisons and anti-MDR agents
• Protein kinase C θ (PKCθ) inhibitors
• Piperidine carboxamide as transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists
• Potent and selective blockers of the Nav1.8 sodium channel as potential analgesics for the treatment of neuropathic and inflammatory pain
• 5,6-fused heteroaromatic ureas as TRPV1 antagonists
• Allosteric enhancers of the A3 adenosine receptor
• Human liver glycogen phosphorylase (HLGP) inhibitors for the treatment of type 2 diabetes

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302,H315,H319,H335
• Conseils de prudence: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves