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182028

Sigma-Aldrich

Poly(ethylene oxide)

average MV 600,000 (nominal), powder, hydroxyl, BHT as inhibitor

Synonyme(s) :

Polyethylene oxide, PEO

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About This Item

Formule linéaire :
(-CH2CH2O-)n
Numéro CAS:
25322-68-3
Numéro MDL:
MFCD00081839
Code UNSPSC :
12352104
ID de substance PubChem :
24850972
Nomenclature NACRES :
NA.23

product name

Poly(ethylene oxide), average Mv 600,000 (nominal), powder

Forme

powder

Niveau de qualité

100

Poids mol.

average Mv 600,000 (nominal)

Contient

200-500 ppm BHT as inhibitor

Viscosité

4,500-8,800 cP, 5 % in H2O(25 °C, Brookfield)(lit.)

Température de transition

Tm 65 °C

Extrémité Ω

hydroxyl

Extrémité α

hydroxyl

Application(s)

battery manufacturing

Chaîne SMILES 

[H]OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Clé InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Description générale

Poly(ethylene oxide)(PEO) is a high molecular weight, non-ionic water-soluble polymer. It forms agel on hydration and shows good swelling capacity. PEO polymers are non-toxicand widely used in drug delivery systems to enhance drug solubility.

Application

Poly(ethylene oxide) can be used to prepare:
  • Bioabsorbable and injectable hydrogels for sustained drug release.
  • PEO/graphene oxide composite electrolyte membrane for fuel cells.
  • Poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO-b-PCL) diblock copolymer. Losartan potassium encapsulated (PEO-b-PCL) copolymer can be used as a drug carrier.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Jun Li et al.
Journal of biomedical materials research. Part A, 65(2), 196-202 (2003-05-08)
Polymeric hydrogels long have attracted interest for biomaterials applications because of their generally favorable biocompatibility. High in water content, they are particularly attractive for delivery of delicate bioactive agents, such as proteins. However, because they require covalent crosslinking for gelation
Angeliki Chroni et al.
Nanomaterials (Basel, Switzerland), 10(9) (2020-09-24)
We report on the preparation of drug nanocarriers by encapsulating losartan potassium (LSR) into amphiphilic block copolymer micelles, utilizing the biocompatible/biodegradable poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO-b-PCL) diblock copolymer. The PEO-b-PCL micelles and LSR-loaded PEO-b-PCL nanocarriers were prepared by organic solvent evaporation method
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
M Patel Geeta et al.
Current drug delivery, 6(2), 159-165 (2009-05-20)
Carbamazepine indicated for the control of epilepsy, undergoes extensive hepatic first-pass metabolism after oral administration. A vaginal dosage form of carbamazepine is not commercially available. Conventional suppository having poor retention in the vaginal tract, as they are removed in a
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Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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