PARP1
poly (ADP-ribose) polymerase 1
Synonymes:
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1
Espèce(s):
Human PARP1 (142), Mouse Parp1 (11545), Rat Parp1 (25591), Thale Cress PARP1 (817690), chicken PARP1 (396199), Zebrafish parp1 (560788), sheep PARP1 (100135697), domestic cat PARP1 (101081434), Horse PARP1 (100058523), dog PARP1 (490385) ...Plus
ID UniProtKB:
ID du gène:
- Human(142) Summary: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
- Mouse(11545) poly (ADP-ribose) polymerase family, member 1
- Rat(25591) poly (ADP-ribose) polymerase 1
- Thale Cress(817690) poly [ADP-ribose] polymerase 2
- chicken(396199) poly (ADP-ribose) polymerase 1
- Zebrafish(560788) poly (ADP-ribose) polymerase family, member 1
- sheep(100135697) poly (ADP-ribose) polymerase 1
- domestic cat(101081434) poly (ADP-ribose) polymerase 1
- Horse(100058523) poly (ADP-ribose) polymerase 1
- dog(490385) poly (ADP-ribose) polymerase 1
- domestic guinea pig(100733925) poly (ADP-ribose) polymerase 1
- naked mole-rat(101703207) poly (ADP-ribose) polymerase 1
- cow(286764) poly (ADP-ribose) polymerase 1
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-PARP (Cleaved-Asp214) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
western blot
western blot
Anticorps anti-poly(ADP-ribose), clone 10H, clone 10H, from mouse,
Espèces réactives
human
Application
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Monoclonal Anti-PARP1 antibody produced in mouse, clone 3G4, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-PARP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-cleaved PARP-1 Antibody, clone 2G13 Antibody, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, monkey
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Small Molecule - Inhibitor
Référence du produit
Description
Espèce(s)
Nicotinamide, BioReagent, suitable for cell culture, suitable for insect cell culture,
Espèce(s)
human
Proteins
Référence du produit
Description
Espèce(s)
PARP1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Espèce(s)
human
Monoclonal Anti-PARP1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2220, purified immunoglobulin, buffered aqueous glycerol solution,
Espèce(s)
human
Monoclonal Anti-PARP1, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2209, purified immunoglobulin, buffered aqueous glycerol solution,
Espèce(s)
human