Recombinant protein encoding amino acids 1-140 of the large subunit of human DNA polymerase d.
Application
For WB: Use at a concentration of 1:1,000. Predicted molecular weight: 130 kDa. Optimal dilutions/concentrations should be determined by the reseracher.
Biochem/physiol Actions
DNA polymerase d (delta) functions in DNA replication and DNA repair. It also possesses 3′ to 5′ exonuclease activity. In leading strand synthesis it requires the processivity factor, PCNA. It is also possibly involved in the completion of DNA synthesis during Okazaki fragment elongation following the initiation of synthesis by the DNA polymerase a/primase complex
Features and Benefits
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Physical form
Phosphate-buffered saline, pH 7.2, containing no preservatives
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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