Skip to Content
Merck
All Photos(3)

Key Documents

E6632

Sigma-Aldrich

Epoxy-activated-Agarose

lyophilized powder

Sign Into View Organizational & Contract Pricing

Select a Size

1 G
CHF 186.00
5 G
CHF 709.00

CHF 186.00

Estimated to ship on17 April 2025

All Photos(3)

Select a Size

Change View
1 G
CHF 186.00
5 G
CHF 709.00

About This Item

MDL number:
MFCD00163561
UNSPSC Code:
23151817
NACRES:
NA.56

CHF 186.00

Estimated to ship on17 April 2025

form

lyophilized powder

Quality Level

200

extent of labeling

≥20 μmol per mL

technique(s)

affinity chromatography: suitable

matrix

cross-linked 4% beaded agarose

matrix active group

epoxy

matrix attachment

through epoxy to hydroxyl

matrix spacer

12 atoms

swelling

1 g swells to ~3 mL

suitability

suitable for chromatography

storage temp.

−20°C

Looking for similar products? Visit Product Comparison Guide

General description

Epoxy-activated-Agarose is a resin. Ligands can be covalently linked to agarose via the interaction of the nucleophilic groups of the ligand with the epoxy group.[1]
when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether.

Application

Epoxy-activated-Agarose is a lyophilized powder, stabilized with lactose, which is used in affinity chromatography, protein chromatography and activated/functionalized matrices. Epoxy-activated agarose has been used in studies informing anti-proliferative activity on human-derived cancer cells as well as cancer prevention.

Other Notes

Ligand: 1,4-bis(2:3-Epoxypropoxy)butane
Attachment: one epoxy group
Spacer: provides a 12-atom spacer when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether.

Physical form

Lyophilized powder stabilized with lactose

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000399835
0000372964
0000372964
0000399835
0000324782

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Adel M Nour et al.
Infection and immunity, 77(3), 1262-1271 (2009-01-07)
Multiple microbial components trigger the formation of an inflammasome complex that contains pathogen-specific nucleotide oligomerization and binding domain (NOD)-like receptors (NLRs), caspase-1, and in some cases the scaffolding protein ASC. The NLR protein Nalp1b has been linked to anthrax lethal
J J Malinowski et al.
Protein science : a publication of the Protein Society, 4(10), 2149-2155 (1995-10-01)
Interleukin-1 beta converting enzyme (ICE) is a cysteine protease that catalyzes the conversion of the inactive precursor form of IL-1 beta to an active mature form. The mature form of IL-1 beta is involved in mediating inflammatory responses and in
G J Fennington et al.
Microbiology (Reading, England), 142 ( Pt 2), 321-330 (1996-02-01)
The Rhizobium leguminosarum bv. trifolii BAL fructokinase (frk) gene was isolated on a 2 center dot 4 kb BamHI fragment from the cosmid pLA72 by complementation analysis of the Tn5-induced frk mutant BAL79, and confirmed by hybridization analysis. The nucleotide
Donald Voet and Judith G. Voet
Biochemistry (2004)
Zhirong Wang et al.
Biochemical and biophysical research communications, 323(3), 743-749 (2004-09-24)
The phytochemical resveratrol (trans-3,4',5-trihydroxystilbene) is a naturally occurring polyphenol with a plethora of health-beneficial properties, including a preventive role in cancer. We surmise that resveratrol may exert its diverse biological effects by interacting with specific target proteins, denoted RTPs. To
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service