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Anticonvulsant hypersensitivity syndrome (AHS): a case report.

Tennessee medicine : journal of the Tennessee Medical Association (2013-04-27)
Bradley R Keel, Catherine L Payne
ZUSAMMENFASSUNG

Anticonvulsant Hypersensitivity Syndrome (AHS) is a rare complication of common drugs used today. It is unusual in that it occurs later than most other drug reactions, about two to six weeks after initiation of the offending agent. It also has a hereditary background unlike most other drug reactions. This reaction is caused by the aromatic amines and causes hepatitis, skin rash, fever, and other systemic organ involvement can occur. The reaction is rare but often fatal, thus the observer should be acutely aware of this in the months following initiation of the agents.

MATERIALIEN
Produktnummer
Marke
Produktbeschreibung

Sigma-Aldrich
5,5-Diphenylhydantoin, ≥98%
Supelco
Phenytoin, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
Phenytoin -Lösung, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
Phenytoin, European Pharmacopoeia (EP) Reference Standard
Phenytoin für die Systemeignung, European Pharmacopoeia (EP) Reference Standard