1600201

Regorafenib

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): Regorafenib Monohydrat, 4-[4-[[[[4-Chlor-3-(trifluormethyl)-phenyl]-amino]-carbonyl]-amino]-3-fluorphenoxy]-N-methyl-2-pyridincarboxamid Monohydrat
• Empirische Formel (Hill-System): C₂₁H₁₅ClF₄N₄O₃ · H₂O
• CAS-Nummer: 1019206-88-2
• Molekulargewicht: 500.83
• MDL number: MFCD17170366
• UNSPSC Code: 41116107
• NACRES: NA.24

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• API family: regorafenib
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 15-25°C
• SMILES string: FC(F)(F)c1c(ccc(c1)NC(=O)Nc2c(cc(cc2)Oc3cc(ncc3)C(=O)NC)F)Cl.O
• InChI: 1S/C21H15ClF4N4O3.H2O/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26;/h2-10H,1H3,(H,27,31)(H2,29,30,32);1H2
• InChI key: ZOPOQLDXFHBOIH-UHFFFAOYSA-N

Beschreibung

General description

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Application

Regorafenib USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS08,GHS09
• signalword: Warning
• hcodes: H361fd,H373,H410
• pcodes: P202 - P260 - P273 - P280 - P308 + P313 - P391
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2
• target_organs: Liver
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable