1466696

N-Nitrosomethylaminobutyric Acid (NMBA)

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): 4-[Methyl(nitroso)amino]butanoic acid
• Empirische Formel (Hill-System): C₅H₁₀N₂O₃
• CAS-Nummer: 61445-55-4
• Molekulargewicht: 146.14
• MDL number: MFCD00869939
• UNSPSC Code: 41116107
• NACRES: NA.24

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• packaging: pkg of 1 mg
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecules)
• format: neat
• storage temp.: −20°C
• SMILES string: N(N=O)(CCCC(=O)O)C
• InChI: 1S/C5H10N2O3/c1-7(6-10)4-2-3-5(8)9/h2-4H2,1H3,(H,8,9)
• InChI key: SJLBIPLIGYWGJV-UHFFFAOYSA-N

Beschreibung

General description

Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.

This product is provided as delivered and specified by the issuing Pharmacopoeia. For further information and support, including certificate/ product information sheets, please go to the website of the issuing Pharmacopoeia.

Application

N-Nitrosomethylaminobutyric Acid (NMBA) USP reference standard is intended for use only as specifically prescribed in the United States Pharmacopoeia.

It is also used to prepare standard, nitrosamine standards stock solution mixture, and sensitivity solutions to determine NMBA impurity in drug substances and drug products (valsartan, irbesartan, and losartan potassium etc) by chromatography according to general chapter <1469> of United States Pharmacopeia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H302 + H312 + H332,H319
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Lagerklasse: 3 - Flammable liquids
• wgk: WGK 2
• flash_point_f: 35.6 °F
• flash_point_c: 2 °C