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SML0340

Sigma-Aldrich

Hydroxy-Dynasore

≥98% (HPLC)

Synonym(e):

3-Hydroxy-2-naphthalenecarboxylic acid 2-[(2,4,5-trihydroxyphenyl)methylene]hydrazide, 3-Hydroxy-N′-[(2,4,5-trihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide

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About This Item

Empirische Formel (Hill-System):
C18H14N2O5
CAS-Nummer:
1256493-34-1
Molekulargewicht:
338.31
MDL-Nummer:
MFCD23704787
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329825345
NACRES:
NA.77

Qualitätsniveau

100

Assay

≥98% (HPLC)

Form

powder

Lagerbedingungen

protect from light

Farbe

faintly yellow to dark yellow

Löslichkeit

DMSO: >10 mg/mL

Lagertemp.

2-8°C

SMILES String

Oc1cc(O)c(\C=N\NC(=O)c2cc3ccccc3cc2O)cc1O

InChI

1S/C18H14N2O5/c21-14-8-17(24)16(23)7-12(14)9-19-20-18(25)13-5-10-3-1-2-4-11(10)6-15(13)22/h1-9,21-24H,(H,20,25)/b19-9+

InChIKey

UAXHPUSKEWEOAP-DJKKODMXSA-N

Biochem./physiol. Wirkung

Hydroxy-Dynasore is a cell permeable and potent dynamin inhibitor that prevents uptake of recombinant botulinum neurotoxin A heavy chain binding domain (BoNT/A-Hc). Apparently, Hydroxy-Dynasore prevents dynamin-mediated fission of endocytic vesicles from the plasma membrane.

Sonstige Hinweise

Air sensitive.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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