D6513

Desmosterol

≥84% (GC)

• Synonym(e): 24-Dehydrocholesterol, 3β-Hydroxy-5,24-cholestadiene, 5,24-Cholestadien-3β-ol
• Empirische Formel (Hill-System): C₂₇H₄₄O
• CAS-Nummer: 313-04-2
• Molekulargewicht: 384.64
• EG-Nummer: 206-236-2
• MDL-Nummer: MFCD00056432
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24894033
• NACRES: NA.77

Eigenschaften

• Assay: ≥84% (GC)
• Form: powder
• Lagertemp.: −20°C
• SMILES String: [H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC=C(C)C
• InChI: 1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9,19,21-25,28H,6,8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
• InChIKey: AVSXSVCZWQODGV-DPAQBDIFSA-N

Beschreibung

Allgemeine Beschreibung

Desmosterol is a C27 sterol intermediate in cholesterol synthesis. It may be associated with the pathogenesis of Alzheimer′s disease (AD).

Anwendung

Desmosterol has been used as a standard for the estimation of the concentrations of cholesterol and plant sterols. It has also been used to suppress nigericin-induced sterol regulatory element-binding proteins 2 (SREBP2) maturation.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)