C4282

Coenzym A Hydrat

≥85% (UV, HPLC)

• Synonym(e): CoA
• Empirische Formel (Hill-System): C₂₁H₃₆N₇O₁₆P₃S · xH₂O
• CAS-Nummer: 85-61-0
• Molekulargewicht: 767.53 (anhydrous basis)
• Beilstein: 77809
• MDL-Nummer: MFCD06795839
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24892684
• NACRES: NA.21

Eigenschaften

• Biologische Quelle: yeast
• Assay: ≥85% (UV, HPLC)
• Form: powder
• Funktionelle Gruppe: phospholipid
• Versandbedingung: ambient
• Lagertemp.: −20°C
• SMILES String: O.CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n2cnc3c(N)ncnc23)[C@@H](O)C(=O)NCCC(=O)NCCS
• InChI: 1S/C21H36N7O16P3S.H2O/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28;/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35);1H2/t11-,14-,15-,16+,20-;/m1./s1
• InChIKey: TVSAELAFGDOPKI-BLPRJPCASA-N

Beschreibung

Anwendung

Coenzyme A hydrate has been used in the thiolase enzyme assay of recombinant acetoacetyl-CoA thiolase (rACAT) in Clonorchis sinensis. It may be used as a reference standard in Raman spectra measurements.

Biochem./physiol. Wirkung

Coenzyme A (CoA) is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP. CoA plays important roles in many metabolic pathways, including the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. One of the main functions of CoA is the carrying and transfer of acyl groups. Acylated deriviates, for example acetyl-CoA, are critical intermediates in many metabolic reactions. CoA levels can be altered during starvation, and in conditions such as cancer, diabetes, and alcoholism.

Vorsicht

The free acid is less stable than the sodium or lithium salt; 5% decomposition may occur within 6 months when stored at −80 °C.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable