B3563

Bifonazol

≥98% (HPLC)

• Synonym(e): 1-(p,α-Diphenylbenzyl)-imidazol
• Empirische Formel (Hill-System): C₂₂H₁₈N₂
• CAS-Nummer: 60628-96-8
• Molekulargewicht: 310.39
• NACRES: NA.77
• PubChem Substance ID: 329773219
• UNSPSC Code: 12352200
• EC Number: 262-336-6
• MDL number: MFCD00865567
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• solubility: DMSO: >10 mg/mL
• originator: Bayer
• storage temp.: room temp
• SMILES string: c1ccc(cc1)C(c2ccc(cc2)-c3ccccc3)n4ccnc4
• InChI: 1S/C22H18N2/c1-3-7-18(8-4-1)19-11-13-21(14-12-19)22(24-16-15-23-17-24)20-9-5-2-6-10-20/h1-17,22H
• InChI key: OCAPBUJLXMYKEJ-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Bifonazol ein Imidazol-basiertes Antipilzmittel mit einem breiten Wirkspektrum gegen viele Pilze, Schimmel, Hefen und einige Gram-positive Bakterien. Bifonazol hemmt Ergosterol Biosynthetic Protein 28 und Cytochrom P450 2B4.

Bifonazole is used to treat several infections such as onychomycoses, otomycoses, erythrasma, psoriasis, sebopsoriasis, seborrhoeic dermatitis and rosacea.[1] Bifonazole is also used as an important drug to treat melanoma.

Features and Benefits

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable