A2836

Ansamitocin P-3 from Actinosynnema pretiosum

≥90% (HPLC)

• Empirische Formel (Hill-System): C₃₂H₄₃ClN₂O₉
• CAS-Nummer: 66584-72-3
• Molekulargewicht: 635.14
• NACRES: NA.32
• PubChem Substance ID: 24890696
• UNSPSC Code: 12352202
• MDL number: MFCD00274586
• Form: powder
• Assay: ≥90% (HPLC)

Eigenschaften

• Quality Segment: 200
• assay: ≥90% (HPLC)
• form: powder
• storage temp.: 2-8°C
• SMILES string: CO[C@@H]1\C=C\C=C(C)\Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)C[C@H](OC(=O)C(C)C)[C@]3(C)O[C@@H]3[C@H](C)[C@@H]4C[C@@]1(O)NC(=O)O4
• InChI: 1S/C32H43ClN2O9/c1-17(2)29(37)43-25-15-26(36)35(6)21-13-20(14-22(40-7)27(21)33)12-18(3)10-9-11-24(41-8)32(39)16-23(42-30(38)34-32)19(4)28-31(25,5)44-28/h9-11,13-14,17,19,23-25,28,39H,12,15-16H2,1-8H3,(H,34,38)/b11-9+,18-10+/t19-,23+,24-,25+,28-,31+,32+/m1/s1
• InChI key: OPQNCARIZFLNLF-KUDLRRJMSA-N

Beschreibung

Biochem/physiol Actions

Fungal metabolite with antineoplastic, antimitotic activity. Binds to tubulin and inhibits vinblastine-induced spiral formation.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H302 + H332,H315,H319,H335
• Sicherheitshinweise: P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklasse: 13 - Non Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Gloves