This product is not tested for solubility. Other Corticosterone products available, such as C2505 and 235135, indicate that this material is soluble in Ethanol at 50 mg/mL. A brief search of this literature indicates that the compound is also soluble in DMSO at 69 mg/mL ( (199.15 mM).
Fortfahren mit
27840
Corticosteron
≥98.5% (HPLC)
Synonym(e):
11β,21-Dihydroxy-4-pregnen-3,20-dion, 11β,21-Dihydroxyprogesteron, 4-Pregnen-11β,21-diol-3,20-dion, Kendall’s Compound B, Reichstein’s Substance H
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| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
100 mg | Warenkorb auf Verfügbarkeit prüfen | CHF 45.40 |
500 mg | Warenkorb auf Verfügbarkeit prüfen | CHF 162.00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C21H30O4
CAS-Nummer:
Molekulargewicht:
346.46
UNSPSC Code:
12352211
NACRES:
NA.77
PubChem Substance ID:
EC Number:
200-019-6
Beilstein/REAXYS Number:
2339601
MDL number:
Technischer Dienst
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Unterstützung erhaltenbiological source
synthetic
Quality Segment
assay
≥98.5% (HPLC)
form
powder or crystals
optical activity
[α]20/D +223±3°, c = 1% in ethanol
mp
179-183 °C
functional group
ketone
SMILES string
C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)CO
InChI
1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1
InChI key
OMFXVFTZEKFJBZ-HJTSIMOOSA-N
Gene Information
human ... EBP(10682), SERPINA6(866)
rat ... Ar(24208), Nr3c1(24413)
General description
Application
Biochem/physiol Actions
Corticosterone is synthesized from cholesterol in the adrenal cortex that activates both mineralocorticoid and glucocorticoid receptors. The role of corticosterones is vital for reproductive processes including ovulation, lutenization, development of oocytes, parturition and lactation. The metabolism of corticosterone is modulated by the enzyme 11β-hydroxysteroid dehydrogenase.[8][9]
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Preparation Note
Corticosterone is soluble in chloroform and ethanol.
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Dieser Artikel | |||
|---|---|---|---|
| biological source synthetic | biological source synthetic (organic) | biological source - | biological source - |
| functional group ketone | functional group - | functional group - | functional group - |
| assay ≥98.5% (HPLC) | assay ≥92% | assay ≥98% (HPLC) | assay ≥95% (HPLC) |
| form powder or crystals | form powder | form - | form crystalline powder |
| mp 179-183 °C | mp 179-183 °C (lit.) | mp 179-183 °C (lit.) | mp - |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
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what is the solubility of Corticosterone in DMSO or ethanol?
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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