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SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

Synonyme:
BAF190, BAF190A, BRG1, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(6597) Summary: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
  • Mouse(20586) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • Rat(171379) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • dog(476710) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • sheep(101116565) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • domestic cat(101097046) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • Zebrafish(353295) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • chicken(395932) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • cow(414274) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • naked mole-rat(101700987) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • domestic guinea pig(100719729) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-BRG1 Antibody, clone 1N12, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, mouse
Anwendung
immunocytochemistry
immunohistochemistry

western blot
Anti-SNF2β/BRG1 Antibody, serum, Upstate®,
Speziesreaktivität
human, mouse, rat
Anwendung
immunoprecipitation (IP)
western blot
Anti-SMARCA4 Antibody, clone 20C3.2, clone 20C3.2, from mouse,
Speziesreaktivität
human, rat
Anwendung
immunocytochemistry
western blot
Anti-SMARCA4 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-BRG1/SMARCA4 Antibody, clone 20C3.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, rat
Anwendung
immunocytochemistry
immunohistochemistry

western blot

Proteins

Produktnummer
Beschreibung
Spezies
BRG1, wild type human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Spezies
human
BRG1 (1480-1603) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human SMARCA4,
Spezies
human