Direkt zum Inhalt
Merck

SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

Synonyme:
PI12, neuroserpin
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(5274) Summary: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(20713) serine (or cysteine) peptidase inhibitor, clade I, member 1
  • Rat(116459) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • dog(478684) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • naked mole-rat(101716288) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • domestic guinea pig(100733658) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • chicken(425002) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • sheep(101122566) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • Horse(100057410) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • Domestic Rabbit(100341797) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • Zebrafish(557627) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • domestic cat(101090383) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • cow(509976) serpin peptidase inhibitor, clade I (neuroserpin), member 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-SERPINI1, (C-terminal) antibody produced in mouse, clone 1E10, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
Anti-Neuroserpin antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
chimpanzee, human, mouse, rat
Anwendung
ELISA
western blot
Anti-SERPINI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
Anti-SERPINI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Monoclonal Anti-SERPINI1 antibody produced in mouse, clone 1D10, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunohistochemistry

western blot

Proteins

Produktnummer
Beschreibung
Spezies
Neuroserpin human, recombinant, expressed in E. coli, ≥96% (SDS-PAGE), ≥96% (HPLC), suitable for cell culture,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human SERPINI1,
Spezies
human
MISSION® esiRNA, targeting mouse Serpini1,
Spezies
mouse