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Merck

PRAME

preferentially expressed antigen in melanoma

Synonyme:
CT130, MAPE, OIP-4, OIP4
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(23532) Summary: This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(75829) preferentially expressed antigen in melanoma
  • Rat(680000) preferentially expressed antigen in melanoma
  • naked mole-rat(101711995) preferentially expressed antigen in melanoma
  • dog(477552) preferentially expressed antigen in melanoma
  • Horse(100061889) preferentially expressed antigen in melanoma
  • domestic cat(101086260) preferentially expressed antigen in melanoma
  • cow(528601) preferentially expressed antigen in melanoma
  • cow(785023) preferentially expressed antigen in melanoma
  • sheep(101108258) preferentially expressed antigen in melanoma
  • domestic guinea pig(100731688) preferentially expressed antigen in melanoma

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-PRAME antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-PRAME antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
ANTI-MAPE(C-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
flow cytometry
immunohistochemistry

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human PRAME,
Spezies
human
MISSION® esiRNA, targeting mouse Prame,
Spezies
mouse