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Merck

PDE1A

phosphodiesterase 1A, calmodulin-dependent

Synonyme:
CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(5136) Summary: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]
  • Mouse(18573) phosphodiesterase 1A, calmodulin-dependent
  • Rat(81529) phosphodiesterase 1A, calmodulin-dependent
  • chicken(424116) phosphodiesterase 1A, calmodulin-dependent
  • Zebrafish(564465) phosphodiesterase 1A, calmodulin-dependent
  • domestic cat(101083101) phosphodiesterase 1A, calmodulin-dependent
  • dog(403652) phosphodiesterase 1A, calmodulin-dependent
  • naked mole-rat(101712147) phosphodiesterase 1A, calmodulin-dependent
  • sheep(101119369) phosphodiesterase 1A, calmodulin-dependent
  • Domestic Rabbit(100346878) phosphodiesterase 1A, calmodulin-dependent
  • cow(281969) phosphodiesterase 1A, calmodulin-dependent
  • Horse(100054082) phosphodiesterase 1A, calmodulin-dependent
  • domestic guinea pig(100527956) phosphodiesterase 1A, calmodulin-dependent

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-PDE1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-PDE1A antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot
Anti-PDE1A antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, mouse
Anwendung
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
Spezies
human
Vinpocetin, ≥98%, solid,
Spezies
human
Dipyridamol, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Dipyridamol-Unreinheit Standard, British Pharmacopoeia (BP) Reference Standard,
Spezies
human
Dipyridamol, British Pharmacopoeia (BP) Reference Standard,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
PDE1A Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human PDE1A,
Spezies
human
MISSION® esiRNA, targeting mouse Pde1a,
Spezies
mouse