Direkt zum Inhalt
Merck

IL10RA

interleukin 10 receptor, alpha

Synonyme:
CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3587) Summary: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]
  • Mouse(16154) interleukin 10 receptor, alpha
  • Rat(117539) interleukin 10 receptor, alpha
  • sheep(101120946) interleukin 10 receptor, alpha
  • domestic guinea pig(100727507) interleukin 10 receptor, alpha
  • dog(610823) interleukin 10 receptor, alpha
  • naked mole-rat(101706532) interleukin 10 receptor, alpha
  • Zebrafish(777651) interleukin 10 receptor, alpha
  • domestic cat(101087601) interleukin 10 receptor, alpha
  • cow(513478) interleukin 10 receptor, alpha
  • chicken(419771) interleukin 10 receptor, alpha

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-Interleukin-10 Receptor α antibody produced in mouse, clone 37607, purified immunoglobulin, lyophilized powder,
Speziesreaktivität
human
Anwendung
neutralization
Anti-IL-10R α antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence

western blot
Monoclonal Anti-IL10RA antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL8203, purified immunoglobulin, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
western blot
Anti-IL10RA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot
Anti-IL10RA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence