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IFNL3

interferon, lambda 3

Synonyme:
IL-28B, IL28B, IL28C
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(282617) Summary: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
  • Mouse(338374) interferon lambda 3
  • Rat(685840) interferon, lambda 3
  • naked mole-rat(101697684) interferon, lambda 3

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