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GRM7

glutamate receptor, metabotropic 7

Synonyme:
GLUR7, GPRC1G, MGLU7, MGLUR7
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2917) Summary: L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
  • Mouse(108073) glutamate receptor, metabotropic 7
  • Rat(81672) glutamate receptor, metabotropic 7
  • Zebrafish(564461) glutamate receptor, metabotropic 7
  • chicken(416112) glutamate receptor, metabotropic 7
  • Horse(100052696) glutamate receptor, metabotropic 7
  • domestic cat(101090088) glutamate receptor, metabotropic 7
  • Domestic Rabbit(100343810) glutamate receptor, metabotropic 7
  • cow(535362) glutamate receptor, metabotropic 7
  • dog(484674) glutamate receptor, metabotropic 7

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
O-Phospho-L-Serin, ,
Spezies
human
trans-(±)-ACPD monohydrate, solid, ≥97% (NMR),
Spezies
human
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Spezies
rat, human
L-Glutaminsäure, ReagentPlus®, ≥99% (HPLC),
Spezies
rat, human
L-Glutaminsäure, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Spezies
rat, human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
DL-2-Amino-3-Phosphonopropionsäure, ,
Spezies
human
L-Glutaminsäure, ReagentPlus®, ≥99% (HPLC),
Spezies
rat, human
L-Glutaminsäure, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Spezies
rat, human
L-Glutaminsäure, BioUltra, ≥99.5% (NT),
Spezies
rat, human
L-Glutaminsäure, FCC,
Spezies
rat, human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-mGluR7-Antikörper, Upstate®, from rabbit,
Speziesreaktivität
rat
Anwendung
western blot
Anti-GRM7 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

western blot
Anti-MGLUR7 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry

western blot
Monoclonal Anti-GRM7 antibody produced in mouse, clone 1H5, ascites fluid,
Speziesreaktivität
human
Anwendung
ELISA
western blot
Anti-Metabotropic Glutamate Receptor 7 Antibody, Chemicon®, from rabbit,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Spezies
rat, human
L-Glutaminsäure, ReagentPlus®, ≥99% (HPLC),
Spezies
rat, human
L-Glutaminsäure, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Spezies
rat, human
L-Glutaminsäure, BioUltra, ≥99.5% (NT),
Spezies
rat, human
L-Glutaminsäure, FCC,
Spezies
rat, human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Ak032068,
Spezies
mouse
MISSION® esiRNA, targeting human GRM7,
Spezies
human