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GEMIN2

gem (nuclear organelle) associated protein 2

Synonyme:
SIP1, SIP1-delta
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(8487) Summary: This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011]
  • Mouse(66603) gem (nuclear organelle) associated protein 2
  • Rat(84404) gem (nuclear organelle) associated protein 2
  • domestic cat(101083009) gem (nuclear organelle) associated protein 2
  • domestic guinea pig(100732674) gem (nuclear organelle) associated protein 2
  • naked mole-rat(101715665) gem (nuclear organelle) associated protein 2
  • sheep(101122894) gem (nuclear organelle) associated protein 2
  • dog(610087) gem (nuclear organelle) associated protein 2
  • Zebrafish(550271) gem (nuclear organelle) associated protein 2
  • chicken(423336) gem (nuclear organelle) associated protein 2
  • cow(510259) gem (nuclear organelle) associated protein 2

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Gemin2-Antikörper, Klon 2E17, clone 2E17, from mouse,
Speziesreaktivität
human, mouse
Anwendung
ELISA
immunocytochemistry

immunoprecipitation (IP)

western blot
Anti-GEMIN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-GEMIN2 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-GEMIN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human GEMIN2,
Spezies
human