Direkt zum Inhalt
Merck

CNTNAP2

contactin associated protein-like 2

Synonyme:
AUTS15, CASPR2, CDFE, NRXN4, PTHSL1
Spezies:
Human CNTNAP2 (26047), Mouse Cntnap2 (66797), Rat Cntnap2 (500105), Horse CNTNAP2 (100060296), Domestic Rabbit CNTNAP2 (100354524), chicken CNTNAP2 (768456), sheep CNTNAP2 (101106322), dog CNTNAP2 (100687859), domestic cat CNTNAP2 (101086795), cow CNTNAP2 (100337375) ...Mehr
UniProtKB-ID:
Q9UHC6, D3DWG2, Q14DG2, Q52LV1, Q5H9Q7, Q9UQ12
Gen-ID:
  • Human(26047) Summary: This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation.[provided by RefSeq, Mar 2010]
  • Mouse(66797) contactin associated protein-like 2
  • Rat(500105) contactin associated protein-like 2
  • Horse(100060296) contactin associated protein-like 2
  • Domestic Rabbit(100354524) contactin associated protein-like 2
  • chicken(768456) contactin associated protein-like 2
  • sheep(101106322) contactin associated protein-like 2
  • dog(100687859) contactin associated protein-like 2
  • domestic cat(101086795) contactin associated protein-like 2
  • cow(100337375) contactin associated protein-like 2
  • cow(516395) contactin associated protein-like 2
  • domestic guinea pig(100717858) contactin associated protein-like 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Produktnummer
Beschreibung
Spezies
RAB1315
Human Caspr2 ELISA, for serum, plasma and cell culture supernatants,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
ABN1380
Anti-Caspr2 Antibody, extracellular domain, serum, from rabbit,
Speziesreaktivität
human, mouse
Anwendung
immunocytochemistry
western blot
HPA002739
Anti-CNTNAP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
SAB1407277
Anti-CNTNAP2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot
SAB1410493
Anti-CNTNAP2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot
C8737
Anti-Caspr2 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
EHU157191
MISSION® esiRNA, targeting human CNTNAP2,
Spezies
human
EMU003431
MISSION® esiRNA, targeting mouse Cntnap2,
Spezies
mouse