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CDK9

cyclin-dependent kinase 9

Synonyme:
C-2k, CDC2L4, CTK1, PITALRE, TAK
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(1025) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]
  • Mouse(107951) cyclin-dependent kinase 9 (CDC2-related kinase)
  • Rat(362110) cyclin-dependent kinase 9
  • domestic guinea pig(100725846) cyclin-dependent kinase 9
  • naked mole-rat(101722666) cyclin-dependent kinase 9
  • sheep(101109788) cyclin-dependent kinase 9
  • Zebrafish(321602) cyclin-dependent kinase 9 (CDC2-related kinase)
  • cow(520580) cyclin-dependent kinase 9
  • dog(491325) cyclin-dependent kinase 9
  • chicken(417226) cyclin-dependent kinase 9
  • fruit fly(37586) Cyclin-dependent kinase 9
  • domestic cat(101097767) cyclin-dependent kinase 9

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CDK9, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-CDK9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
Anti-CDK9 Antibody, clone 1F9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, monkey, mouse, rat
Anwendung
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-phospho-CDK9 (pThr186) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot
Rabbit anti-CDK9 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Speziesreaktivität
human, mouse
Anwendung
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Flavopiridol -hydrochlorid, ≥98% (HPLC), powder,
Spezies
human
Roscovitine, ≥98% (TLC),
Spezies
human, mouse, rat
Olomoucine, ≥98% (HPLC),
Spezies
human, rat

Proteins

Produktnummer
Beschreibung
Spezies
Cdk9/Cyclin-T1-Protein, aktiv, 10 µg, Active, C-terminal 6His-tagged, full length recombinant, human Cdk9 co-expressed with untagged, full-length human Cyclin T1, for use in Kinase Assays.,
Spezies
human
CDK9/CyclinK, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human CDK9,
Spezies
human