CDK8
cyclin-dependent kinase 8
Synonyme:
K35
Spezies:
Human CDK8 (1024), Mouse Cdk8 (264064), domestic guinea pig Cdk8 (100718250), naked mole-rat Cdk8 (101719987), sheep CDK8 (101115551), Domestic Rabbit CDK8 (100353845), domestic cat CDK8 (101086278), Zebrafish cdk8 (373868), cow CDK8 (507149), dog CDK8 (486035) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(1024) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. [provided by RefSeq, Jul 2008]
- Mouse(264064) cyclin-dependent kinase 8
- domestic guinea pig(100718250) cyclin-dependent kinase 8
- naked mole-rat(101719987) cyclin-dependent kinase 8
- sheep(101115551) cyclin-dependent kinase 8
- Domestic Rabbit(100353845) cyclin-dependent kinase 8
- domestic cat(101086278) cyclin-dependent kinase 8
- Zebrafish(373868) cyclin-dependent kinase 8
- cow(507149) cyclin-dependent kinase 8
- dog(486035) cyclin-dependent kinase 8
- chicken(428080) cyclin-dependent kinase 8
- Horse(100050819) cyclin-dependent kinase 8
- fruit fly(39157) Cyclin-dependent kinase 8
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CDK8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot
western blot
ANTI-CDK8 antibody produced in mouse, clone 5H4, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
western blot
Anti-CDK8 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse
Anwendung
ELISA
western blot
western blot
Anti-CDK8, affinity isolated antibody,
Speziesreaktivität
human, mouse
Anwendung
immunohistochemistry
Anti-CDK8 antibody produced in rabbit, IgG fraction of antiserum,
Speziesreaktivität
bovine, dog, horse, human, mouse, pig, rabbit
Anwendung
western blot
Small Molecule - Inhibitor
Produktnummer
Beschreibung
Spezies