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CASP6

caspase 6, apoptosis-related cysteine peptidase

Synonyme:
MCH2
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(839) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(12368) caspase 6
  • Rat(83584) caspase 6
  • dog(487899) caspase 6, apoptosis-related cysteine peptidase
  • Zebrafish(552927) caspase 6, apoptosis-related cysteine peptidase
  • chicken(395477) caspase 6, apoptosis-related cysteine peptidase
  • naked mole-rat(101707090) caspase 6, apoptosis-related cysteine peptidase
  • domestic guinea pig(100713360) caspase 6, apoptosis-related cysteine peptidase
  • cow(538409) caspase 6, apoptosis-related cysteine peptidase
  • sheep(101119820) caspase 6, apoptosis-related cysteine peptidase
  • domestic cat(768261) caspase 6, apoptosis-related cysteine peptidase

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
ANTI-PHOSPHO-CASPASE 6(S257) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-CASP6 (Cleaved-Asp162) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
mouse, rat
Anwendung
ELISA
immunohistochemistry

western blot
Anti-CASP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-CASP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-Caspase 6 (pSer257) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
N-Acetyl-Val-Glu-Ile-Asp-al, ~99% (HPLC), powder,
Spezies
human
Caspase Inhibitor, ,
Spezies
human
NSCI, ≥97% (HPLC), solid,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human CASP6,
Spezies
human
MISSION® esiRNA, targeting mouse Casp6,
Spezies
mouse