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C4A

complement component 4A (Rodgers blood group)

Synonyme:
C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(720) Summary: This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  • Mouse(625018) complement component 4A (Rodgers blood group)
  • Rat(24233) complement component 4A (Rodgers blood group)
  • Horse(100059239) complement component 4A (Rodgers blood group)
  • dog(481722) complement component 4A (Rodgers blood group)
  • naked mole-rat(101719002) complement component 4A (Rodgers blood group)
  • domestic guinea pig(100728345) complement component 4A (Rodgers blood group)
  • Domestic Rabbit(100356976) complement component 4A (Rodgers blood group)
  • sheep(101123672) complement component 4A (Rodgers blood group)
  • cow(280678) complement component 4A

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-C4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-C4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-C4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry

Proteins

Produktnummer
Beschreibung
Spezies
Complement C4 from human serum, ≥300,000 C4H50 units/mg protein,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse C4a (2),
Spezies
mouse
MISSION® esiRNA, targeting mouse C4a (1),
Spezies
mouse