ALDH18A1
aldehyde dehydrogenase 18 family, member A1
Synonyme:
ARCL3A, GSAS, P5CS, PYCS
Spezies:
Human ALDH18A1 (5832), Mouse Aldh18a1 (56454), Rat Aldh18a1 (361755), Zebrafish aldh18a1 (557186), domestic guinea pig Aldh18a1 (100716882), naked mole-rat Aldh18a1 (101713177), Horse ALDH18A1 (100061213), chicken ALDH18A1 (423976), domestic cat ALDH18A1 (101090803), sheep ALDH18A1 (101108974) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(5832) Summary: This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. [provided by RefSeq, Jul 2008]
- Mouse(56454) aldehyde dehydrogenase 18 family, member A1
- Rat(361755) aldehyde dehydrogenase 18 family, member A1
- Zebrafish(557186) aldehyde dehydrogenase 18 family, member A1
- domestic guinea pig(100716882) aldehyde dehydrogenase 18 family, member A1
- naked mole-rat(101713177) aldehyde dehydrogenase 18 family, member A1
- Horse(100061213) aldehyde dehydrogenase 18 family, member A1
- chicken(423976) aldehyde dehydrogenase 18 family, member A1
- domestic cat(101090803) aldehyde dehydrogenase 18 family, member A1
- sheep(101108974) aldehyde dehydrogenase 18 family, member A1
- Domestic Rabbit(100352530) aldehyde dehydrogenase 18 family, member A1
- cow(514759) aldehyde dehydrogenase 18 family, member A1
- dog(477781) aldehyde dehydrogenase 18 family, member A1
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-ALDH18A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ALDH18A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-ALDH18A1 antibody produced in mouse, clone 2B5, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
western blot
Anti-ALDH18A1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, horse, human, pig, rat
Anwendung
western blot
Anti-ALDH18A1 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
bovine, canine, human, mouse, rat
Anwendung
ELISA
western blot
western blot
esiRNA
Produktnummer
Beschreibung
Spezies