T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes.

T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes.

Nature communications (2017-11-28)

Iria Gomez-Tourino, Yogesh Kamra, Roman Baptista, Anna Lorenc, Mark Peakman

RÉSUMÉ

Defects in T cell receptor (TCR) repertoire are proposed to predispose to autoimmunity. Here we show, by analyzing >2 × 10

MATÉRIAUX

Référence du produit

Marque

Description du produit

Sigma-Aldrich

Sérum humain, from human male AB plasma, USA origin, sterile-filtered

Sigma-Aldrich

Staphylococcal enterotoxin B from Staphylococcus aureus