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  • Structural characterization of an immunoenhancing heteroglycan isolated from an aqueous extract of an edible mushroom, Lentinus squarrosulus (Mont.) Singer.

Structural characterization of an immunoenhancing heteroglycan isolated from an aqueous extract of an edible mushroom, Lentinus squarrosulus (Mont.) Singer.

Carbohydrate research (2010-10-12)
Sanjoy Kumar Bhunia, Biswajit Dey, Kankan K Maity, Sukesh Patra, Soumitra Mandal, Swatilekha Maiti, Tapas K Maiti, Samir R Sikdar, Syed S Islam
RÉSUMÉ

A water-soluble polysaccharide, isolated from the hot water extract of the fruiting bodies of an edible mushroom, Lentinus squarrosulus (Mont.) Singer was found to contain d-galactose, l-fucose, and d-glucose in a molar ratio of nearly 1:1:5. Structural investigation of the polysaccharide was carried out using acid hydrolysis, methylation analysis, periodate oxidation study, and NMR experiments ((1)H, (13)C, DQF-COSY, TOCSY, NOESY, ROESY, HMQC, and HMBC). On the basis of above-mentioned experiments, the structure of the repeating unit of the polysaccharide was established as: This polysaccharide showed macrophage as well as splenocyte and thymocyte activation.

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Sigma-Aldrich
Lipopolysaccharides from Salmonella enterica serotype typhimurium, purified by phenol extraction