33429

Doxycycline hyclate

VETRANAL^®, analytical standard

• Synonyme(s) : Chlorhydrate de doxycycline hémiéthanolate hémihydrate
• Formule empirique (notation de Hill) : C₂₂H₂₄N₂O₈ · HCl · 0.5H₂O · 0.5C₂H₆O
• Numéro CAS: 24390-14-5
• Poids moléculaire : 512.94
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329754541
• MDL number: MFCD07357237
• Beilstein/REAXYS Number: 5702728

Propriétés

• grade: analytical standard
• Quality Segment: 100
• agency: EPA 1694
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• solubility: DMSO: soluble 100 mM
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria, mycoplasma, parasites
• application(s): clinical testing
• format: neat
• mode of action: protein synthesis | interferes
• SMILES string: Cl[H].Cl[H].[H]O[H].CCO.C[C@@H]1C2[C@H](O)C3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C2C(=O)c4c(O)cccc14.C[C@@H]5C6[C@H](O)C7[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]7(O)C(O)=C6C(=O)c8c(O)cccc58
• InChI: 1S/2C22H24N2O8.C2H6O.2ClH.H2O/c2*1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;;/h2*4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);3H,2H2,1H3;2*1H;1H2/t2*7-,10?,14?,15-,17-,22-;;;;/m00..../s1
• InChI key: HALQELOKLVRWRI-ZVACAFRPSA-N

Description

General description

Chemical structure: tetracycline

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Mode d'action : L'hyclate de doxycycline inhibe la réponse inflammatoire à l'agent de la maladie de Lyme, le spirochète Borrelia burgdorferi.

Spectre d'activité : Inhibiteur à large spectre des métalloprotéinases matricielles in vivo.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335,H361fd,H412
• pcodes: P202 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves