1.37134

Acétonitrile

EMPROVE^® ESSENTIAL

• Synonyme(s) : ACN, Cyanométhane, Cyanure de méthyle
• Formule linéaire : CH₃CN
• Numéro CAS: 75-05-8
• Poids moléculaire : 41.05
• UNSPSC Code: 12191502
• Beilstein/REAXYS Number: 741857
• MDL number: MFCD00001878

Propriétés

• Quality Segment: 500
• vapor density: 1.41 (vs air)
• vapor pressure: 72.8 mmHg ( 20 °C)
• product line: EMPROVE^® ESSENTIAL
• assay: ≥99.5% (GC)
• form: liquid (colorless)
• autoignition temp.: 973 °F
• expl. lim.: 16 %
• technique(s): API processing | polymorph screening: suitable
• refractive index: n20/D 1.344 (lit.)
• bp: 81-82 °C (lit.)
• mp: −45 °C (lit.)
• density: 0.786 g/mL at 25 °C (lit.)
• application(s): mRNA manufacturing; pharmaceutical
• format: neat
• storage temp.: 2-25°C
• SMILES string: CC#N
• InChI: 1S/C2H3N/c1-2-3/h1H3
• InChI key: WEVYAHXRMPXWCK-UHFFFAOYSA-N

Description

General description

We offer a range of high quality critical raw materials, solvents and reagents plus the documentation and expertise to meet stringent regulatory requirements. In addition to our comprehensive portfolio, we also offer custom manufacturing services to meet your exact needs. As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Acetonitrile is relatively inert, due to the strong C-C bond which can only be hydrolyzed under extreme conditions, making it an excellent reaction solvent used in pharma production as a reagent, in the reaction or extraction solvent, starting material to synthesize vitamins A and B1, cortisone, carbonate drugs and some amino acids. Acetonitrile is also used as a solvent in the production of insulin and antibiotics.
Acetonitrile Emprove^® Essential is suitable for pharmaceutical application.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS07
• Mot-clé: Danger
• Mentions de précaution: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Classe de stockage: 3 - Flammable liquids
• Point d'éclair (°F): 35.6 °F - closed cup
• Point d'éclair (°C): 2.0 °C - closed cup
• Codes de danger: H225,H302 + H312 + H332,H319