104648

Cellvento^® ModiFeed Gal- COMP

Chemically defined cell culture feed - EMPROVE^® CCM

• UNSPSC Code: 41106213

Propriétés

• Nom du produit: Cellvento^® ModiFeed Gal- COMP, Chemically defined cell culture feed- EMPROVE^® CCM, compacted dry powder
• Quality Segment: 500
• description: shipped with cooling packs
• product line: Cellvento^®
• form: compacted dry powder
• greener alternative product characteristics: Design for Energy Efficiency; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• technique(s): cell culture | mammalian: suitable
• application(s): pharma/biopharma processes
• greener alternative category: DfS-Developed
• storage temp.: 2-8°C

Description

General description

Cellvento^® ModiFeed Gal- COMP is part of the ModiFeed platform. It is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode, while simultanously reducing galactosylation on the protein of interest. It is recommened in combination with the production media Cellvento^® 4CHO and EX-CELL^® Advanced CHO Fed-batch medium or other production media.

We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This product is a Design for Sustainability (DfS) developed product. Click here to view its DfS scorecard.

Application

Glycosylation is known to have effects on the biological activity, solubility, serum half-life, and saftey of therapeutic proteins. Control of protein glycosylation processes, such as galactosylation, while maximizing productivity is key for successful mAb process development and production. Cellvento^® ModiFeed Gal- COMP was developed to increase G0(F), while maintaining or improving titer in CHO fed-batch processes.

Features and Benefits

• Reduced complexity in fed-batch process
• Complete feed maximizing galactosylation
• Highly concentrated to reduce required feed volume
• Compacted format for conventient handling
• Higher liquid feed stability at room temperature

Preparation Note

Formulated to contain 143.6 grams of powder per liter of feed.

Legal Information

CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3