T3577

Tolperisone hydrochloride

≥98% (HPLC), ion channel blocker , solid

• Synonyme(s) : 2-Methyl-1-(4-methylphenyl)-3-(1-piperidyl)propan-1-one hydrochloride
• Formule empirique (notation de Hill) : C₁₆H₂₃NO · HCl
• Numéro CAS: 3644-61-9
• Poids moléculaire : 281.82
• NACRES: NA.77
• PubChem Substance ID: 329826771
• UNSPSC Code: 12352200
• EC Number: 222-876-5
• MDL number: MFCD00058211
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: desiccated

Propriétés

• Nom du produit: Tolperisone hydrochloride, ≥98% (HPLC), solid
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• color: white
• solubility: H₂O: >20 mg/mL
• storage temp.: room temp
• SMILES string: Cl.CC(CN1CCCCC1)C(=O)c2ccc(C)cc2
• InChI: 1S/C16H23NO.ClH/c1-13-6-8-15(9-7-13)16(18)14(2)12-17-10-4-3-5-11-17;/h6-9,14H,3-5,10-12H2,1-2H3;1H
• InChI key: ZBUVYROEHQQAKL-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Tolperisone is an ion channel blocker and centrally acting muscle relaxant.

Tolperisone regulates ionic currents in myelinates axons and subsequently decreases excitability and mediates its antispastic functions³.

Tolperisone is derived from piperidine and possesses membrane stabilizing action. It helps in reducing the effect of spasticities associated with the nervous and muscular system. It exhibits muscle relaxant action through attenuating voltage-gated sodium channels in the brain stem.

Preparation Note

Tolperisone hydrochloride dissolves in water at a concentration that is greater than 20 mg/ml.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mot-clé: Warning
• Codes de danger: H302 + H312 + H332
• Mentions de précaution: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): dust mask type N95 (US), Eyeshields, Gloves