T1126
Thyroglobulin from porcine thyroid gland
powder
Synonyme(s) :
TG human
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About This Item
Numéro CAS:
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.61
Produits recommandés
Source biologique
Porcine thyroid
Forme
powder
Poids mol.
~670 kDa
Composition
Iodine, ≥0.3%
Dosage de l'azote
14.0-17.5% total
Technique(s)
protein purification: suitable
Cendres
≤4%
pl
4.58
Numéro d'accès UniProt
Température de stockage
−20°C
Informations sur le gène
pig ... TG(100156471)
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Actions biochimiques/physiologiques
Thyroglobulin has been shown to regulate the transcription of iodide porters including sodium iodide symporter and pendrin.
Thyroglobulin is a major protein involved with iodine metabolism. It consists of an iodine-containing protein that is stored in the thyroid gland and is converted into circulating thyroxines when the thyroid is stimulated by TSH (Thyroid Stimulating Hormone) from the pituitary. Thyroglobulin is often used as a carrier protein for the production of antibodies. Its advantage as a carrier protein comes from its large number of tyrosine residues that can be used for conjugation using the diazo reaction.
Autres remarques
Electrophoretically heterogeneous.
Notes préparatoires
When reconstituted in water (20 mg/ml), a turbid solution with some insolubles is observed.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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