SML1623

MSP-3

≥98% (HPLC)

• Synonyme(s) : N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide
• Formule empirique (notation de Hill) : C₁₆H₁₉NO₃S
• Numéro CAS: 1820968-63-5
• Poids moléculaire : 305.39
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825508
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: oil

Propriétés

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: oil
• color: white to beige
• storage temp.: room temp
• SMILES string: O=C(NCC1=CC=C(O)C(OC)=C1)CCCC2=CC=CS2
• InChI: 1S/C16H19NO3S/c1-20-15-10-12(7-8-14(15)18)11-17-16(19)6-2-4-13-5-3-9-21-13/h3,5,7-10,18H,2,4,6,11H2,1H3,(H,17,19)
• InChI key: HCUVEUVIUAJXRB-UHFFFAOYSA-N

Description

Biochem/physiol Actions

MSP-3 is a Transient Receptor Potential Vanilloid Type-1 (TRPV1) channel agonist with antioxidant and neuroprotective activity. MSP-3 activated TRPV1 channels with similar efficacy as compared to capsaicin (EC50 = 870 nM). It protected a keratinocyte cell line from oxidative stress damage with more efficacy than capsaicin and prevented the damage caused by H2O2 in differentiated human neuroblastoma cell lines as well as in rat cortical slices.

TRPV1 agonist protective against oxidative stress

Informations sur la sécurité

• Pictogrammes: GHS07
• Mot-clé: Warning
• Codes de danger: H315,H319
• Mentions de précaution: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable