SML0812

NBD-556

≥98% (HPLC)

• Synonyme(s) : N1-(4-Chlorophenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)-ethanediamide
• Formule empirique (notation de Hill) : C₁₇H₂₄ClN₃O₂
• Numéro CAS: 333353-44-9
• Poids moléculaire : 337.84
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Propriétés

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 15 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: Clc1ccc(cc1)NC(=O)C(=O)NC2CC(NC(C2)(C)C)(C)C
• InChI: 1S/C17H24ClN3O2/c1-16(2)9-13(10-17(3,4)21-16)20-15(23)14(22)19-12-7-5-11(18)6-8-12/h5-8,13,21H,9-10H2,1-4H3,(H,19,22)(H,20,23)
• InChI key: ZKXLQCIOURANAD-UHFFFAOYSA-N

Description

Biochem/physiol Actions

NBD-556 is small molecule mimetic of CD4 that recognizes the HIV-1 envelope protein gp120.

NBD-556 is small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding. The CD4-induced conformational change in gp120 is necessary for interaction with CCR5.

Informations sur la sécurité

• Pictogrammes: GHS06
• Mot-clé: Danger
• Codes de danger: H301
• Mentions de précaution: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable