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Key Documents

SAB1305560

Sigma-Aldrich

MONOCLONAL ANTI-ERK1/2 antibody produced in mouse

clone 784CT7.6.3, IgG fraction of antiserum, buffered aqueous solution

Synonyme(s) :

ERK1, MAPK3, Mitogen-activated protein kinase 3, PRKM3

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

IgG fraction of antiserum

Type de produit anticorps

primary antibodies

Clone

784CT7.6.3, monoclonal

Forme

buffered aqueous solution

Poids mol.

43136 Da

Espèces réactives

mouse, human

Technique(s)

western blot: 1:1000

Isotype

IgG2a

Numéro d'accès UniProt

P27361,P28482

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... MAPK3(5595)

Forme physique

Supplied in PBS with 0.09% (W/V) sodium azide

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Guangchao Zhao et al.
Rejuvenation research, 22(4), 325-334 (2018-11-10)
It is known that preconditional treatment with volatile anesthetics can induce tolerance of the brain to stroke. A previous study demonstrated that the involvement of TREK-1, a two-pore domain K+ channel, in sevoflurane preconditioning induced neuroprotection against focal cerebral ischemia
Tingting Zhang et al.
Molecular genetics & genomic medicine, 9(5), e1643-e1643 (2021-03-26)
Neurofibromatosis type 1 is an autosomal dominant inherited disease and caused by NF1 gene mutation. Its clinical manifestations include multiple cafe´-au lait (CAL) spots, skinfold freckling, neurofibroma, bone dysplasia, learning disabilities, and an increased risk of malignancy. Here, we reported
Davide D'Amico et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 42(2), 462-472 (2016-08-19)
The inability to properly extinguish fear memories constitutes the foundation of several anxiety disorders, including panic disorder. Recent findings show that boosting prefrontal cortex synaptic plasticity potentiates fear extinction, suggesting that therapies that augment synaptic plasticity could prove useful in
Marisa Schmitt et al.
Molecular & cellular proteomics : MCP, 18(6), 1096-1109 (2019-03-21)
Targeted inhibition of mutated kinases using selective MAP kinase inhibitors in malignant melanoma often results in temporary improvement of clinical symptoms followed by rapid development of resistance. To gain insights in molecular processes that govern resistance, we performed SILAC-based quantitative
Yuhang Yuan et al.
Cell cycle (Georgetown, Tex.), 17(11), 1390-1402 (2018-06-29)
Necrotizing enterocolitis (NEC) is a potentially fatal illness in premature neonates. Tumor necrosis factor-α (TNF-α) and autophagy are associated with the pathogenesis of NEC. This study aimed to explore whether TNF-α might regulate apoptosis in neonatal NEC model cells IEC-6
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