S0508

Sulfamonomethoxine

• Synonyme(s) : 4-Amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfonamide, 4-Methoxy-6-sulfanilamidopyrimidine, N¹-(6-Methoxy-4-pyrimidinyl)sulfanilamide, SMM
• Formule empirique (notation de Hill) : C₁₁H₁₂N₄O₃S
• Numéro CAS: 1220-83-3
• Poids moléculaire : 280.30
• UNSPSC Code: 51283946
• NACRES: NA.85
• PubChem Substance ID: 24899439
• MDL number: MFCD00063466
• Beilstein/REAXYS Number: 621128

Propriétés

• form: powder
• Quality Segment: 200
• color: white to yellow-white
• solubility: methanol: soluble 10 mg/mL
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria, parasites
• mode of action: DNA synthesis | interferes, enzyme | inhibits
• SMILES string: COc1cc(NS(=O)(=O)c2ccc(N)cc2)ncn1
• InChI: 1S/C11H12N4O3S/c1-18-11-6-10(13-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,14,15)
• InChI key: WMPXPUYPYQKQCX-UHFFFAOYSA-N

Description

General description

Chemical structure: sulfonamide

Application

Sulfamonomethoxine is used to study degradation by Fe³O⁴ magnetic nanoparticles. It is used in blood kinetic studies and is used to study capsule formation of Bordetella bronchiseptica.

Biochem/physiol Actions

Sulfamonomethoxine is a competitive inhibitor of dihydropteroate synthetase used to block the synthesis of folic acid.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H317,H319,H335
• pcodes: P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves