P3510

Papaverine hydrochloride

≥98% (titration by HCL04), powder, cerebral vasodilator

• Synonyme(s) : 6,7-Dimethoxy-1-veratrylisoquinoline hydrochloride
• Formule empirique (notation de Hill) : C₂₀H₂₁NO₄ · HCl
• Numéro CAS: 61-25-6
• Poids moléculaire : 375.85
• MDL number: MFCD00012745
• NACRES: NA.77
• PubChem Substance ID: 24278152
• UNSPSC Code: 41106305
• EC Number: 200-502-1
• Beilstein/REAXYS Number: 3921435
• Assay: ≥98%
• Form: powder

Propriétés

• Nom du produit: Papaverine hydrochloride, powder
• assay: ≥98%
• Quality Segment: 100
• form: powder
• color: white
• solubility: H₂O: 25 mg/mL
• SMILES string: COC1=C(OC)C=C(C(CC2=CC(OC)=C(OC)C=C2)=NC=C3)C3=C1.Cl
• InChI: 1S/C20H21NO4.ClH/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16;/h5-8,10-12H,9H2,1-4H3;1H
• InChI key: UOTMYNBWXDUBNX-UHFFFAOYSA-N
• Gene Information: human ... PDE4B(5142)

Description

General description

Papaverine hydrochloride belongs to the group of benzylisoquinoline alkaloid. It is obtained from opium poppy.

Application

Papaverine hydrochloride has been used:

• in oxygenated Krebs solution for tissue mechanics analysis
• as a vasodilator in heparinized horse serum in tissue uptake technique
• as an inhibitor of H-MPP+ uptake into stably transfected 293 cells expressing either extraneuronal monoamine transporter (EMT) human or EMT rat

Biochem/physiol Actions

Papaverine is originally used to resolve male impotence.

Smooth muscle relaxant and cerebral vasodilator; phosphodiesterase inhibitor.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves