M3778

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride

≥97% (GC), MAO-A inhibitor, powder

• Synonyme(s) : Clorgyline
• Formule empirique (notation de Hill) : C₁₃H₁₅Cl₂NO · HCl
• Numéro CAS: 17780-75-5
• Poids moléculaire : 308.63
• NACRES: NA.77
• PubChem Substance ID: 24278179
• UNSPSC Code: 12352116
• EC Number: 241-760-5
• MDL number: MFCD00052012
• eCl@ss: 32150312
• Assay: ≥97% (GC)
• Form: powder

Propriétés

• Nom du produit: N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride, ≥97% (GC)
• Quality Segment: 100
• assay: ≥97% (GC)
• form: powder
• solubility: DMSO: 10 mg/mL, clear, colorless to faintly yellow
• storage temp.: 2-8°C
• SMILES string: Cl.CN(CCCOc1ccc(Cl)cc1Cl)CC#C
• InChI: 1S/C13H15Cl2NO.ClH/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15;/h1,5-6,10H,4,7-9H2,2H3;1H
• InChI key: BBAZDLONIUABKI-UHFFFAOYSA-N
• Gene Information: human ... MAOA(4128) ; rat ... Maoa(29253), Maob(25750)

Description

Application

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride has been used as a monoamine oxidase A (MAO-A) inhibitor:

• in MAO-A biochemical assay
• to study its effects on the transit of serotonin (5-HT) in the human placenta explants
• to study its effects on human prostate cancer cells

Biochem/physiol Actions

MAO-A inhibitor.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Pictogrammes: GHS06
• Mot-clé: Danger
• Codes de danger: H301,H312 + H332
• Mentions de précaution: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Oral
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• EPI (équipement de protection individuelle): dust mask type N95 (US), Eyeshields, Faceshields, Gloves