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GW20086F

Sigma-Aldrich

Anti-Human IgM antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Anti-Immunoglobulin M

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About This Item

Numéro MDL:
MFCD00162468
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

chicken

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Espèces réactives

human

Fabricant/nom de marque

Genway 15-288-20086F

Technique(s)

western blot: suitable

Numéro d'accès UniProt

P01871

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... IGHM(3507)

Immunogène

Human IgM native protein.

Application

Anti-Human IgM antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Actions biochimiques/physiologiques

Ig μ chain C region is a protein encoded by the IGHM gene in humans and is expressed on the surface of T cells. It is associated with agammaglobulinemia-1. Immunoglobulin is expressed in epithelial cell and plays a role in growth and survival. IgG heavy chain is expressed in acute myeloid leukemia (AML). IgM derived from AML might be a novel AML-related molecule that is involved in leukemogenesis and AML progression. It may serve as a useful molecular marker for designing targeted therapy and monitoring minimal residual disease. Elevated levels of soluble IGM Ligand (sCD40L) were found in serum of patients with chronic spontaneous urticaria (CU).

Forme physique

Solution in phosphate buffered saline containing 0.02% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Jing Huang et al.
Cellular & molecular immunology, 11(1), 94-104 (2013-10-22)
Immunoglobulin (Ig), a characteristic marker of B cells, has been reported to be expressed in epithelial cells, with a suggested role in their growth and survival. We have previously reported that IgG heavy chain is expressed in acute myeloid leukemia
T Jasinska et al.
BioMed research international, 2013, 823798-823798 (2013-11-16)
Elevated levels of soluble CD40 Ligand (sCD40L) were found in serum but not in plasma of patients with chronic spontaneous urticaria (CU). What is important is that sCD40L has proinflammatory properties, and its elevated plasma level may indicate increased risk

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