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G0885

Sigma-Aldrich

Glycogen from bovine liver

≥85% dry basis (enzymatic)

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About This Item

Formule linéaire :
(C6H10O5)n
Numéro CAS:
9005-79-2
Numéro CE :
232-683-8
Numéro MDL:
MFCD00081547
Code UNSPSC :
12352201
Nomenclature NACRES :
NA.25
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Source biologique

bovine liver

Niveau de qualité

200

Essai

≥85% dry basis (enzymatic)

Forme

powder

Couleur

white to off-white

Température de stockage

2-8°C

InChI

1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-20(45-23-17(36)12(31)10(29)6(2-26)42-23)14(33)18(37)24(43-8)44-19-7(3-27)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21+,22+,23-,24-/m1/s1

Clé InChI

BYSGBSNPRWKUQH-UJDJLXLFSA-N

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Catégories apparentées

Description générale

Glycogen is a branched polymer of glucose synthesized by animal cells for energy storage and release. It is constructed of predominantly α1→4 glycosidic bonds with branches created through α1→6 glycosidic bonds.

Application

Glycogen from bovine liver may be used in carbohydrate storage and metabolism research and to study various enzymes such as alpha-glucosidase(s) (GAA) and glycogen phosphorylase(s) (GPase).[1] Glycogen may be used as a substrate to identify and characterize its metabolizing enzymes.[1]

Notes préparatoires

Prepared by a modification of the procedure of Bell, et al., Biochem. J., 28, 882 (1934).

Autres remarques

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
0000367342
0000367344
0000315782
0000315788
0000315781

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Istvan Katona et al.
Orphanet journal of rare diseases, 9, 17-17 (2014-02-06)
Glycogenosis type II or Pompe disease is an autosomal-recessive lysosomal storage disease due to mutations in the gene encoding acid alpha-glucosidase (GAA), an enzyme required for lysosomal glycogen degradation. The disease predominantly affects the skeletal and respiratory muscles but there
Louise Knudsen et al.
PloS one, 7(12), e51972-e51972 (2013-01-10)
Insulin can trigger metabolic as well as mitogenic effects, the latter being pharmaceutically undesirable. An understanding of the structure/function relationships between insulin receptor (IR) binding and mitogenic/metabolic signalling would greatly facilitate the preclinical development of new insulin analogues. The occurrence
Sonya V Iverson et al.
Free radical biology & medicine, 63, 369-380 (2013-06-08)
Besides helping to maintain a reducing intracellular environment, the thioredoxin (Trx) system impacts bioenergetics and drug metabolism. We show that hepatocyte-specific disruption of Txnrd1, encoding Trx reductase-1 (TrxR1), causes a metabolic switch in which lipogenic genes are repressed and periportal
Marion Curtis et al.
Cell metabolism, 29(1), 141-155 (2018-09-04)
Successful metastasis requires the co-evolution of stromal and cancer cells. We used stable isotope labeling of amino acids in cell culture coupled with quantitative, label-free phosphoproteomics to study the bidirectional signaling in ovarian cancer cells and human-derived, cancer-associated fibroblasts (CAFs) after
Maria Kylä-Puhju et al.
Meat science, 69(1), 143-149 (2005-01-01)
The activity of glycogen debranching enzyme (GDE) was studied in relation to pH value and temperature in porcine masseter and longissimus dorsi muscles. A glycogen limit dextrin was used as the substrate for GDE, and the enzyme was derived from
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Questions

1–4 of 4 Questions  

  1. What is the specific rotation of Product G0885, Glycogen from Bovine Liver?

    1 answer

    1. The specific rotation of this product is +196° to +197°.

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  2. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  3. What is the solubility of Product G0885, Glycogen from Bovine Liver?

    1 answer

    1. Sigma routinely tests the solubility in water at 50 mg/mL, yielding a hazy solution. In general, glycogens are soluble in water with opalescence and insoluble in alcohol.

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  4. What are glycogens?

    1 answer

    1. Per Biochemistry, Lehninger ed., 2nd ed, p. 266: A general description of glycogens is: A polymer of alpha (1->4) linked D-Glucose with alpha (1->6) branching at about ever 8 to 12 glucose residues. The molecular weight for bovine source is not mentioned, but glycogen in general is 270,000-3.5 million.

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