C6277

Congo Red

Dye content, ≥85%, certified by the Biological Stain Commission, powder

• Synonyme(s) : Congo Red 4B, Cosmos Red, Cotton Red B, Cotton Red C, Direct Red 28, Direct Red R, Direct Red Y
• Formule empirique (notation de Hill) : C₃₂H₂₂N₆Na₂O₆S₂
• Numéro CAS: 573-58-0
• Poids moléculaire : 696.66
• UNSPSC Code: 12171500
• NACRES: NA.47
• PubChem Substance ID: 24892852
• EC Number: 209-358-4
• MDL number: MFCD00004028
• Colour Index Number: 22120
• Beilstein/REAXYS Number: 3894858

Propriétés

• Nom du produit: Congo Red, certified by the BSC, BioXtra
• agency: certified by the BSC
• Quality Segment: 200
• product line: BioXtra
• form: powder
• composition: Dye content, ≥85%
• technique(s): microbe id | staining: suitable
• mp: >360 °C (lit.)
• solubility: H₂O: 10 mg/mL
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: [Na+].[Na+].Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c3ccc(cc3)-c4ccc(cc4)\N=N\c5cc(c6ccccc6c5N)S([O-])(=O)=O
• InChI: 1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2/b37-35+,38-36+;;
• InChI key: IQFVPQOLBLOTPF-HKXUKFGYSA-L

Description

Application

Congo red has been used for the staining of β amyloid peptides.

Certified for use as a counterstain for alum based hematoxylin and in the Highman or the Churukian modification of Puchtler′s amyloid stain.

Biochem/physiol Actions

Congo red is a benzidine-based anionic diazo dye. It is a histological dye which binds to many amyloid proteins and is used for the quantification of amyloid β-peptide aggregation. Congo red also interacts with β-D-glucans, polysaccharides containing continuous β-(1→4)-linked D-glucopyranosyl units and some hemicellulosic galactoglucomannans.

Informations sur la sécurité

• pictograms: GHS08
• signalword: Danger
• hcodes: H350,H361d
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Carc. 1B - Repr. 2
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges