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B7688

Sigma-Aldrich

PiB

≥98% (HPLC)

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About This Item

Formule empirique (notation de Hill):
C22H18N2O8
Numéro CAS:
64005-90-9
Poids moléculaire :
438.39
Numéro MDL:
MFCD00333607
Code UNSPSC :
12352200
ID de substance PubChem :
329773301
Nomenclature NACRES :
NA.77

Niveau de qualité

100

Pureté

≥98% (HPLC)

Forme

powder

Couleur

white to light brown

Solubilité

DMSO: 1-2 mg/mL (warmed)

Température de stockage

2-8°C

Chaîne SMILES 

O=C(C1=C2C(C3=CC=C24)=C(C(N(CC(OCC)=O)C3=O)=O)C=C1)N(CC(OCC)=O)C4=O

InChI

1S/C22H18N2O8/c1-3-31-15(25)9-23-19(27)11-5-7-13-18-14(8-6-12(17(11)18)20(23)28)22(30)24(21(13)29)10-16(26)32-4-2/h5-8H,3-4,9-10H2,1-2H3

Clé InChI

WNKQGFNIIHNGQM-UHFFFAOYSA-N

Actions biochimiques/physiologiques

PiB is an inhibitor of the peptidylprolyl isomerase Pin-1. Inhibition of Pin-1 leads to destabilization of the transcription factor Nanog, which is required for maintenance of embryonic stem cell cultures.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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