Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
A5960
Acide L-ascorbique
BioXtra, ≥99.0%, crystalline
Synonyme(s) :
Acide L-thréoascorbique, Facteur anti-scorbut, Vitamine C
About This Item
Produits recommandés
Gamme de produits
BioXtra
Niveau de qualité
Essai
≥99.0%
Forme
crystalline
Technique(s)
cell culture | mammalian: suitable
Impuretés
≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter
Résidus de calcination
≤0.1%
Couleur
white to off-white
pH
1.0-2.5 (25 °C, 176 g/L in water)
Pf
190-194 °C (dec.)
Solubilité
H2O: 0.5 M, clear, colorless
Traces d'anions
sulfate (SO42-): ≤0.05%
Traces de cations
Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%
Chaîne SMILES
OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
InChI
1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
Clé InChI
CIWBSHSKHKDKBQ-JLAZNSOCSA-N
Informations sur le gène
human ... SLC23A2(9962)
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Description générale
Application
- L'acide L-ascorbique a été utilisé pour induire la différenciation ostéoblastique dans des primocultures de moelle osseuse.[4]
- Il a permis d'induire la différenciation de progéniteurs de cardiomyocytes humains (cellules hCMPC) en cardiomyocytes.[5]
- Il a été utilisé pour mesurer l'activité de la chaîne mitochondriale de transport d'électrons (complexe IV).[6]
Actions biochimiques/physiologiques
Attention
Produit(s) apparenté(s)
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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Certificats d'analyse (COA)
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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Is L-ascorbic acid, Product A5960, the same as vitamin C?
1 answer-
Yes, L-ascorbic acid is a synonym for vitamin C.
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What is the extinction coefficient of L-ascorbic acid, Product A5960?
1 answer-
According to the Data for Biochemical Research, 3rd ed., Dawson, R. M. C., et al., Oxford University Press (New York, NY 1986), p. 116, the L-ascorbic acid extinction coefficient: EmM = 7.0 (265 nm, water), 7.5 (245 nm, acid).
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What is the solution stability of L-ascorbic acid, Product A5960?
1 answer-
Aqueous solutions are stable only in the absence of oxygen. Aqueous solutions are most stable at pH 5-6, very unstable at alkaline pH. (Data for Biochemical Research, 3rd ed., Dawson, R. M. C., et al., Oxford University Press (New York, NY: 1986), p. 116) Degradation is markedly increased in the presence of transition metal ions, especially Cu(II) and Fe(III). The first stage of oxidation of L-ascorbic acid to dehydroascorbic acid is reversible and the biological activity is retained. Further oxidation to 2,3-diketogulonic acid is not reversible and the activity is lost. (Omura, H., and Yamafuji, K., in Methodicum Chimicum, 11(2), Korte, F., and Goto, M., eds., Academic Press (New York, NY: 1977), p. 115).
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What is the pKa of L-ascorbic acid, Product A5960?
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The pKa values for L-ascorbic acid (from the chemicals encyclopedia published by the Royal Society of Chemistry) are 4.17 and 11.57.
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