A4403

Acide L-ascorbique

powder, suitable for cell culture, γ-irradiated

• Synonyme(s) : Acide L-thréoascorbique, Facteur anti-scorbut, Vitamine C
• Formule linéaire : C₆H₈O₆
• Numéro CAS: 50-81-7
• Poids moléculaire : 176.12
• UNSPSC Code: 12352207
• NACRES: NA.75
• PubChem Substance ID: 24890857
• EC Number: 200-066-2
• Beilstein/REAXYS Number: 84272
• MDL number: MFCD00064328
• Form: powder

Propriétés

• biological source: synthetic (organic)
• Quality Segment: 200
• sterility: γ-irradiated
• form: powder
• mol wt: M_w 176.12 g/mol
• technique(s): cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable
• color: white to off-white
• pH: 1.0-2.5 (25 °C, 176 g/L in water)
• mp: 190-194 °C (dec.)
• solubility: H₂O: 10 mg/mL
• storage temp.: room temp
• SMILES string: OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
• InChI: 1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
• InChI key: CIWBSHSKHKDKBQ-JLAZNSOCSA-N
• Gene Information: human ... SLC23A2(9962)

Description

General description

Listen to an Audio Overview
L-ascorbic acid is an unsaturated γ-lactone ring containing an enediol configuration (–COH=COH) attached with a carbonyl group.

Application

For use in cell culture applications as an antioxidant and to regenerate tocopherol.
L-ascorbic acid has been used:

• in an osteogenic supplement for the growth of cells
• as a component in the differentiation media
• in WS-MSCs (Werner syndrome-mesenchymal stem cells) to study rescuing properties of ascorbic acid on aging defects

Biochem/physiol Actions

L-ascorbic acid mainly exhibits antioxidant properties. It protects plants from oxidative stress and mammals from diseases associated with oxidative stress. L-ascorbic acid mainly protects from hydroxyl radicals, superoxide and singlet oxygen. In addition, it also reduces the membrane-linked antioxidant α-tocopherol (oxidised form). L-Ascorbic acid enhances endothelium-dependent vasodilation in various disorders, including diabetes, coronary artery disease, hypertension and chronic heart failure.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)