75632
Osmium tetroxide solution
suitable for electron microscopy, 4% in H2O
Synonyme(s) :
Osmium(IV) oxide
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A propos de cet article
Formule linéaire :
OsO4
Numéro CAS:
Poids moléculaire :
254.23
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Form:
solution
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solution
Quality Segment
reaction suitability
reagent type: oxidant
concentration
4% in H2O
technique(s)
electron microscopy: suitable
color
colorless to yellow
pH
6.0-8.0
density
1.0 g/mL at 20 °C
application(s)
hematology
histology
storage temp.
2-8°C
SMILES string
O=[Os](=O)(=O)=O
InChI
1S/4O.Os
InChI key
VUVGYHUDAICLFK-UHFFFAOYSA-N
Application
Osmium tetroxide solution has been used as a fixative in scanning and transmission electron microscopy.
Biochem/physiol Actions
Osmium tetroxide is also referred to as osmium and is mainly used as a secondary fixative of tissues. The molecule reacts with lipid moieties and is responsible for the oxidation of unsaturated bonds of fatty acids. This reaction adds density and contrast to biological samples. In normal tissues, presence of osmium results in intense black staining which can be viewed by normal eye. In addition, it can be used as a mordant (a molecule which combines with stain or dye at later stages) in electron microscopy, thereby enhancing lead staining.
Packaging
5 mL in ampule
10 mL in ampule
10 mL in ampule
Other Notes
Due to the hazardous nature of osmium tetroxide, it is recommended to use an ampule opener when using this chemical.
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Mot-clé
Danger
Codes de danger
Mentions de précaution
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
Classe de stockage
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
Que se passe-t-il ?
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
EPI (équipement de protection individuelle)
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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