A9797

Ambroxol hydrochloride

analytical standard

• Synonyme(s) : 2-Amino-3,5-dibromo-N-(trans-4-hydroxycyclohexyl)benzylamine
• Formule empirique (notation de Hill): C₁₃H₁₈Br₂N₂O · HCl
• Numéro CAS: 23828-92-4
• Poids moléculaire : 414.56
• Numéro CE : 245-899-2
• Numéro MDL: MFCD00078932
• Code UNSPSC : 41116107
• ID de substance PubChem : 329771060
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• Durée de conservation: limited shelf life, expiry date on the label
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: Cl.Nc1c(Br)cc(Br)cc1CN[C@@H]2CC[C@@H](O)CC2
• InChI: 1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H/t10-,11-;
• Clé InChI: QNVKOSLOVOTXKF-PFWPSKEQSA-N

Description

Description générale

Ambroxol hydrochloride is a mucolytic expectorant and a metabolite of bromhexine. It is used in the treatment of respiratory disorders characterized by viscous or excessive mucus.

Application

Ambroxol hydrochloride standard may be used as a reference standard in the determination of ambroxol hydrochloride in pharmaceutical preparations using reversed-phase sequential injection chromatography (RP-SIC) and reversed-phase high performance liquid chromatography (RP-HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Actions biochimiques/physiologiques

Metabolite of bromhexine.
A Nav1.8-preferring sodium channel blocker

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves