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Principaux documents

17343

Sigma-Aldrich

Bromhexine hydrochloride

≥98.0% (AT)

Synonyme(s) :

2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzylamine hydrochloride, N-(2-Amino-3,5-dibromobenzyl)-N-methylcyclohexylamine hydrochloride, Bromohexine hydrochloride

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About This Item

Formule empirique (notation de Hill):
C14H20Br2N2 · HCl
Numéro CAS:
Poids moléculaire :
412.59
Beilstein:
4848376
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22
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Niveau de qualité

Essai

≥98.0% (AT)

Forme

powder

Groupe fonctionnel

amine
bromo

Chaîne SMILES 

Cl.CN(Cc1cc(Br)cc(Br)c1N)C2CCCCC2

InChI

1S/C14H20Br2N2.ClH/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17;/h7-8,12H,2-6,9,17H2,1H3;1H

Clé InChI

UCDKONUHZNTQPY-UHFFFAOYSA-N

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Description générale

Bromhexine hydrochloride is a bronchial mucolytic[1].

Application

Bromhexine hydrochloride was used in the secretion of pancreatic juice of low viscosity[1].

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Les clients ont également consulté

Tatsuhiro Tsujimoto et al.
Alcoholism, clinical and experimental research, 29(12 Suppl), 272S-276S (2005-12-31)
Abstinence is a prerequisite for the treatment of alcoholic chronic pancreatitis, but there are patients who have repeated attacks because of their inability to abstain and the consequent congestive effects of the continued alcohol intake on pancreatic juice. Bromhexine hydrochloride
Amit Kumar Aggarwal et al.
Drug development and industrial pharmacy, 38(11), 1319-1327 (2012-01-31)
The aim of the present study was to prepare the amino acid prodrugs of bromhexine hydrochloride to improve its solubility. All the prodrugs were synthesized by first reacting bromhexine with tert-butoxycarbonyl (Boc) protected amino acid and then deprotection was carried
J L Vercher-Conejero et al.
Revista espanola de medicina nuclear, 30(2), 97-100 (2010-06-24)
Splenosis is defined as the heterotopic autotransplantation of splenic tissue because of a ruptured spleen due to trauma or surgery. It is a benign and incidental finding, although imaging tests may sometimes orient toward malignancy simulating renal tumors, abdominal lymphomas
Ibrahim El Hachmi et al.
Acta orthopaedica Belgica, 78(5), 694-696 (2012-11-21)
Glomus tumours are benign lesions occurring essentially in the hand, with a predilection for the subungueal area. Even though they have been reported in literature, extradigital localisations of glomus tumours are frequently misdiagnosed; they never lead to bone osteolysis. We
N-X Bonne et al.
Rhinology, 50(2), 211-217 (2012-05-23)
Nasal Glial Heterotopias also called Nasal Gliomas (NG) are rare congenital tumours of the midline frontonasal space arising from a normal neurectodermal tissue entrapped during the closure of the anterior neuropore. Historically, such tumours were approached using a frontal craniotomy.

Questions

  1. What solvent should be used and what stock concentration is recommended?

    1 answer
    1. The solubility of this product has not been determined. However, various sources report that this material is soluble in water at 3.33 mg/mL, in DMSO at 8 – 20 mg/mL, and in ethanol at 2.44 mg/L. Warming and sonication may be required. Stock solutions are reported to be stable at -80°C for 6 months and -20°C for 1 month. This information has not been validated.

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